One: Is it possible to replace only the lock cylinder of a padlock?
Yes.
If the lock mechanism is not damaged, or if you want to replace the lock cylinder for security reasons, you can replace only the cylinder. Furthermore, replacing only the cylinder will be less expensive than replacing the entire lock.

Two. How to replace the lock cylinder of the padlock.
1、Remove the existing lock mechanism.
First, use a Phillips head screwdriver to remove the two mounting screws of the door handle. Remove the interior and exterior handles and organize the associated hardware to prevent loss. Use a screwdriver to remove the lock core cover screws and remove the cover. Some anti-theft door locks do not have a lock core cover. Use a Phillips head screwdriver to remove the locking pin fixing screws in the center of the lock body and place them separately. The locking pin fixing screws are generally located on the center line of the side lock body and are parallel to the bottom of the keyhole. Insert the key and gently rotate it to remove the lock core. Keep the key on the lock core for identification purposes. Before removing, ensure that all locking tongues are retracted.
2、Verify the dimensions of the smart lock.
Compare the lock cylinder, confirming that the dimensions are consistent. After confirming that the dimensions of the new lock cylinder are consistent with the old cylinder (within 3mm), compare the width of the lock cylinder. Installation can only proceed if the dimensions are consistent.
3、Install the lock cylinder.
Install and secure the existing handle panel. Then, insert the lock cylinder from the inside of the door towards the outside. once the cylinder is secured, tighten the cylinder fixing screws. Then, rotate the inner knob to perform locking and unlocking tests. Ensure that the latch can extend and retract smoothly, and then install the outer knob. When installing the outer knob, align the projection with the corresponding mounting slot. Insert the outer knob, which includes fingerprint and password collection, into the cylinder from the outside. Rotate the triangular indicator on the inner knob upwards and the battery compartment opening downwards. Keep the outer knob still, then use a flathead screwdriver to rotate the adjustment bolt counterclockwise through the two openings to securely fix the outer knob. Remove the battery cover with a screwdriver and insert four AA batteries sequentially, then tighten the battery cover. Finally, close the outer cover and the installation is complete.